Google DeepMind has launched AlphaGenome, an advanced AI model designed to predict how DNA mutations affect gene regulation.
AlphaGenome builds on DeepMind's previous work with AlphaFold. It analyzes DNA sequences up to 1 million base pairs to predict molecular properties, including gene initiation, splicing patterns, and protein production.
Trained on extensive public datasets, AlphaGenome addresses limitations in previous genomic prediction models. It aids in understanding genetic disruptions that cause diseases like spinal muscular atrophy.
Dr. Caleb Lareau from Memorial Sloan Kettering Cancer Center noted AlphaGenome's significance, calling it a milestone. DeepMind anticipates AlphaGenome will enhance disease understanding and facilitate the design of synthetic DNA.