Recent studies suggest caffeine may extend cell lifespan through several mechanisms.
Research indicates caffeine activates AMPK, a cellular energy sensor, in fission yeast. This activation may contribute to increased cell longevity.
Caffeine also promotes telomere maintenance in mammalian cells, delaying cellular senescence. This effect was observed in both cultured cells and animal models.
Additionally, caffeine's antioxidant properties protect cells against oxidative stress. This has been linked to extended lifespan in yeast cells.
Caffeine activates autophagy, a cellular process removing damaged components, in human skin cells. This may help maintain cellular health and delay aging.
Further research is needed to fully understand caffeine's impact on human aging and determine optimal intake levels.