Groundbreaking research from Sweden's Karolinska Institutet has identified 12 critical biomarkers associated with a longer lifespan. The study analyzed data from nearly 44,000 individuals, aged 64 to 99, with some data extending up to 35 years, and found that approximately 2.7% of the cohort reached centenarian status.
The findings, published in GeroScience, highlight specific biomarkers that, when maintained at optimal levels, significantly influence longevity. These include markers related to glucose metabolism, kidney function, and iron levels. Elevated levels of glucose, creatinine, and uric acid in middle age were linked to a reduced likelihood of reaching 100, while lower levels of these markers, along with healthy cholesterol and robust kidney function, were associated with extended lifespans. The research suggests that proactive management of these biological markers through informed lifestyle decisions can contribute to a longer and higher-quality life, with centenarians often showing more favorable biomarker profiles even in their 60s.