New Technique Improves Giant Tumor Surgery

Edited by: 🐬Maria Sagir

Researchers at Shanghai Jiao Tong University School of Medicine have developed a new surgical technique, FENCY ligation, combined with preoperative embolization, to treat giant plexiform neurofibromas (PNFs). This innovative approach addresses the challenges of removing these complex vascular tumors, promising better outcomes for patients.

Plexiform neurofibromas are benign tumors linked to neurofibromatosis Type 1 (NF1), a genetic disorder. The tumors' size and vascular nature make surgery difficult. The FENCY ligation technique uses a "fence-like" pattern of sutures to control bleeding during surgery.

The technique was tested on eleven patients with giant PNFs, showing effective tumor removal and improved function. The method is especially useful in difficult areas like the face and neck. This approach could redefine surgical standards for complex tumor resections.

Sources

  • Scienmag: Latest Science and Health News

  • Clinical experiences in precision treatment of giant plexiform neurofibromas of head, face, and neck

  • Genotype–phenotype correlations and treatment innovation of neurofibromatosis type 1 (NF1): Current understanding and perspective

  • Advances in the treatment of intracranial neoplastic lesions in children with neurofibromatosis 1

  • Germline Neurofibromin 1 mutation enhances the anti-tumour immune response and decreases juvenile myelomonocytic leukaemia tumourigenicity

  • Epidemiologic and survival analysis of malignant peripheral nerve sheath tumors in patients with neurofibromatosis type 1

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