Mendel's Pea Genes: Genetic Secrets Unlocked After 160 Years

Edited by: Katia Remezova Cath

Unlocking the genetic basis of Mendel's pea traits enhances crop improvement and disease resistance, benefiting global food security.

A recent study in Nature has finally identified the genetic factors behind all seven traits Gregor Mendel studied in pea plants, completing a 160-year-old puzzle. Mendel's experiments in the 1860s established the foundation of genetics, revealing how traits are inherited. He observed predictable patterns in traits like seed shape and flower color, but the specific genes responsible remained elusive for over a century.

Researchers used next-generation sequencing to analyze the DNA of over 697 pea plant variants. This massive dataset, equivalent to nearly 14 billion pages of text, allowed them to create a comprehensive genetic map. The analysis revealed a more complex population structure within the Pisum genus than previously known.

The study identified new allelic variants for previously characterized traits like seed shape and flower color. For example, a new variant was found that could restore purple flowers in white-flowered plants. The team also pinpointed the genes responsible for pod color, pod shape, and flower position, traits that were previously uncharacterized.

Specifically, they found that a deletion near the ChlG gene disrupts chlorophyll synthesis, causing yellow pods. Changes near the MYB gene and in CLE-peptide-encoding genes resulted in constricted pods. A deletion in the CIK-like-coreceptor-kinase gene, along with a modifier locus, was associated with flowers appearing at the end of the stem.

This detailed genetic map also revealed 72 other agriculturally relevant traits. These include the architectures of the seed, pod, flower, leaf, root, and plant. This wealth of information holds great promise for improving crop yield, enhancing disease resistance, and improving environmental adaptations.

By identifying the genetic basis of Mendel's traits and uncovering new genetic interactions, this research provides valuable tools for crop improvement. This can lead to more resilient and productive crops, benefiting agriculture and food security worldwide.

Sources

  • The Hindu

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